Optimization of the method for analyzing endocytosis of fluorescently tagged molecules: Impact of incubation in the cell culture medium and cell surface wash with glycine-hydrochloric acid buffer

To obtain the therapeutic effect of biological medicines, such as proteins and nucleic acids, these medicines must achieve their intracellular target, such as the cytoplasm, and pass through biological membrane barriers. Endocytosis is an attractive route for the intracellular delivery of such drugs, and various endocytosis inhibitors have been used as tools to study the …

Optimization of the method for analyzing endocytosis of fluorescently tagged molecules: Impact of incubation in the cell culture medium and cell surface wash with glycine-hydrochloric acid buffer Read More »

Systematic review of neighborhood socioeconomic indices studied across the cancer control continuum

Background: There is extensive interest in understanding how neighborhood socioeconomic status (nSES) may affect cancer incidence or survival. However, variability regarding items included and approaches used to form a composite nSES index presents challenges in summarizing overall associations with cancer. Given recent calls for standardized measures of neighborhood sociodemographic effects in cancer disparity research, the …

Systematic review of neighborhood socioeconomic indices studied across the cancer control continuum Read More »

Bioengineering of LAB vector expressing Haemolysin co-regulated protein (Hcp): a strategic approach to control gut colonization of Campylobacter jejuni in a murine model

Background: Campylobacter jejuni (C. jejuni) is accountable for more than 400 million cases of gastroenteritis each year and is listed as a high-priority gut pathogen by the World Health Organization (WHO). Although the acute infection of C. jejuni (campylobacteriosis) is commonly treated with macrolides and fluoroquinolones, the emergence of antibiotic resistance among C. jejuni warrants …

Bioengineering of LAB vector expressing Haemolysin co-regulated protein (Hcp): a strategic approach to control gut colonization of Campylobacter jejuni in a murine model Read More »

First outbreak of multi-drug resistant tuberculosis (MDR-TB) in Denmark involving six Danish-born cases

Background: Denmark is a tuberculosis (TB) and multi-drug resistant (MDR) TB low-incidence country at 5 and 0.05 cases per 100.000 population, respectively. Until 2018, transmission of MDR-TB was nonexistent except for few pairwise related family-cases. In this study we describe the first MDR-TB outbreak in Denmark. Methods: Based on genotyping of all Mycobacterium tuberculosis (Mtb) culture-positive …

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Panbio Nasopharyngeal Testt

Detection of SARS-CoV-2 viral antigen.

Overview To provide an additional layer of protection against COVID-19covid 19 and variants including Omicron, Ontario is launching a holiday testing blitz to offer voluntary rapid antigen screening to individuals free of charge at pop-up sites across the province. This initiative is part of the government’s enhanced COVID-19covid 19 testing strategy to mitigate the increased risk of transmission over the holiday …

Detection of SARS-CoV-2 viral antigen. Read More »

SARS-CoV-2 RBD of Spike protein GH452R.V1, CAL.20C, L452R – lineage B.1.429 – CAL Variant

A new emerging variant of SARS-CoV-2, called CAL.20C or lineage B.1.429, was recently reported in California (USA). Identified by researchers at Cedars-Sinai Medical Center in July 2020, the variant was initially reported as rare only to resurface later that year (October). The most recent reports indicate that CAL.20C is rapidly replacing the old 20G lineage, …

SARS-CoV-2 RBD of Spike protein GH452R.V1, CAL.20C, L452R – lineage B.1.429 – CAL Variant Read More »

InstantBlue

InstantBlue ™ is a ready-to-use Coomassie protein dye for polyacrylamide gels. Its unique mechanism of action stains proteins in 15 minutes leaving a clear background eliminating the need to fix, wash or fade. Ultra-fast staining and one-step procedure High sensitivity with detectable 5 ng bands Bright background with a high signal-to-noise ratio Formulated for safe …

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Improved transport system for Neisseria gonorrhoeae in clinical specimens.

Improved transport system for Neisseria gonorrhoeae in clinical specimens.

Protective transport media have for use to protect Neisseria gonorrhoeae in clinical specimens throughout their transit to the laboratory. In this examine, a CO2- setting chamber, the Jembec chamber, was used for transport of clinical speciments requiring examination for gonococci. The survival of N. gonorrhoeae current in clinical speciments when positioned in Amies charcoal transport medium was …

Improved transport system for Neisseria gonorrhoeae in clinical specimens. Read More »

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