Inter-rater reliability of phenotypes and exploratory genotype-phenotype analysis in inherited hidradenitis suppurativa.

Genotype-phenotype correlation measures the correlation between the presence of a bodily trait with a bunch of comparable mutations however depends on dependable phenotyping.

It can present info on illness pathogenesis, future illness development, severity or exercise. Such indicators could be invaluable in hidradenitis suppurativa (HS).To assess inter-rater reliability (IRR) of HS scientific phenotypes and carry out exploratory genotype-phenotype correlation in circumstances of HS with recognized sequence variants.

METHODSLinkage disequilibrium between variants was assessed. Genotype-phenotype correlations have been explored utilizing Spearman correlation coefficients. IRR was calculated utilizing Cohen’s κ. Correlation between phenotype classifications was assessed utilizing the χ2 statistic.

RESULTSForty-three sequence variants with scientific info have been recognized. Clinical phenotypes have been labeled as LC2 (n = 29; 67%), scarring folliculitis (n = 18; 42%), atypical (n = 38; 88%) and nodular (n = 26; 60%). LC1 phenotype was related to common (χ2 = 41·289, P < 0·001) and typical (χ2 = 29·013, P < 0·001) phenotypes. Cohen’s κ was highest for van der Zee and Jemec (0·815), adopted by Martorell-Calatayud et al. (0·813), Naasan and Affleck (0·774) and Canoui-Poitrine et al. (0·435) classifications.

NFRKB Antibody

E11-17081C 100μg
EUR 225
Description: Available in various conjugation types.

NFRKB Antibody

E38PA1809 100ul
EUR 225
Description: Available in various conjugation types.

NFRKB Antibody

E311019 200ul
EUR 275
Description: Available in various conjugation types.

NFRKB Antibody

1-CSB-PA003423
  • Ask for price
  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFRKB. Recognizes NFRKB from Human, Mouse, Monkey. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/40000

NFRKB antibody

70R-50128 100 ul
EUR 242
Description: Purified Polyclonal NFRKB antibody

NFRKB Antibody

AF9129 200ul
EUR 420

NFRKB Antibody

AF9129-100ul 100ul
EUR 280

NFRKB Antibody

AF9129-200ul 200ul
EUR 350

NFRKB Antibody

8C17081 50ug
EUR 368
Description: NFRKB Antibody

NFRKB Antibody

GWB-ML805D 50ug Ask for price

NFRKB Rabbit pAb

A10124-100ul 100 ul
EUR 369.6

NFRKB Rabbit pAb

A10124-200ul 200 ul
EUR 550.8

NFRKB Rabbit pAb

A10124-20ul 20 ul
EUR 219.6

NFRKB Rabbit pAb

A10124-50ul 50 ul
EUR 267.6

NFRKB Rabbit mAb

A23915 100μL
EUR 778.7
Description: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ERK2ERK1/2 (P27361/P28482).

NFRKB cloning plasmid

CSB-CL757573HU-10ug 10ug
EUR 1644
Description: A cloning plasmid for the NFRKB gene.

NFRKB Blocking Peptide

AF9129-BP 1mg
EUR 234

NFRKB Blocking Peptide

20-abx063003
  • Ask for price
  • Ask for price
  • 1 mg
  • 5 mg

NFRKB Polyclonal Antibody

27297 100ul
EUR 439

NFRKB Polyclonal Antibody

27297-100ul 100ul
EUR 302.4

NFRKB Polyclonal Antibody

27297-50ul 50ul
EUR 224.4

NFRKB Polyclonal Antibody

E910124 100ul
EUR 225
Description: Available in various conjugation types.

NFRKB Polyclonal Antibody

E-AB-90081-120uL 120uL
EUR 320
Description: Unconjugated

NFRKB Polyclonal Antibody

E-AB-90081-200uL 200uL
EUR 530
Description: Unconjugated

NFRKB Polyclonal Antibody

E-AB-90081-60uL 60uL
EUR 200
Description: Unconjugated

NFRKB Polyclonal Antibody

E-AB-90081-each each Ask for price
Description: Unconjugated

Mouse Nfrkb ELISA KIT

ELI-39529m 96 Tests
EUR 1038

Human NFRKB ELISA KIT

ELI-44624h 96 Tests
EUR 988.8

Human NFRKB shRNA Plasmid

20-abx953184
  • Ask for price
  • Ask for price
  • 150 µg
  • 300 µg

Mouse NFRKB shRNA Plasmid

20-abx982184
  • Ask for price
  • Ask for price
  • 150 µg
  • 300 µg

Nfrkb (GFP-tagged) - Mouse nuclear factor related to kappa B binding protein (Nfrkb)

MG211898 10 µg Ask for price

Nfrkb ORF Vector (Rat) (pORF)

ORF071281 1.0 ug DNA
EUR 607.2

Nfrkb (untagged) - Mouse nuclear factor related to kappa B binding protein (Nfrkb), (10ug)

MC205447 10 µg Ask for price

NFRKB ORF Vector (Human) (pORF)

ORF007055 1.0 ug DNA
EUR 114

Nfrkb ORF Vector (Mouse) (pORF)

ORF051325 1.0 ug DNA
EUR 607.2

NFRKB Polyclonal Conjugated Antibody

C27297 100ul
EUR 476.4

Human NFRKB knockout cell line

ABC-KH10074 1 vial Ask for price
Description: Human NFRKB knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Nfrkb (Myc-DDK-tagged) - Mouse nuclear factor related to kappa B binding protein (Nfrkb)

MR211898 10 µg Ask for price

Nfrkb (untagged ORF) - Rat nuclear factor related to kappa B binding protein (Nfrkb), (10 ug)

RN213386 10 µg Ask for price

Human NFRKB knockdown cell line

ABC-KD10074 1 vial Ask for price
Description: Human NFRKB knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human NFRKB Protein Lysate 20ug

IHUNFRKBPLLY20UG each
EUR 361
Description: Human NFRKB Protein Lysate 20ug

NFRKB ELISA Kit (Human) (OKCD01959)

OKCD01959 96 Wells
EUR 997.2
Description: Description of target: Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.127 ng/mL

NFRKB (untagged)-Human nuclear factor related to kappaB binding protein (NFRKB), transcript variant 1

SC325410 10 µg Ask for price

NFRKB (untagged)-Human nuclear factor related to kappaB binding protein (NFRKB), transcript variant 2

SC309921 10 µg Ask for price

OCOA12249-20UG - NFRKB Protein Lysate

OCOA12249-20UG 20ug
EUR 269

NFRKB (GFP-tagged) - Human nuclear factor related to kappaB binding protein (NFRKB), transcript variant 2

RG215038 10 µg Ask for price

NFRKB (GFP-tagged) - Human nuclear factor related to kappaB binding protein (NFRKB), transcript variant 1

RG226572 10 µg Ask for price

Nfrkb (Myc-DDK-tagged ORF) - Rat nuclear factor related to kappa B binding protein (Nfrkb), (10 ug)

RR213386 10 µg Ask for price

NFRKB 3'UTR GFP Stable Cell Line

TU065643 1.0 ml
EUR 1825.2

Nfrkb 3'UTR GFP Stable Cell Line

TU164049 1.0 ml Ask for price

Nfrkb 3'UTR GFP Stable Cell Line

TU263943 1.0 ml Ask for price

OKCD01959-96W - NFRKB ELISA Kit (Human)

OKCD01959-96W 96Wells
EUR 675

Nfrkb sgRNA CRISPR Lentivector set (Rat)

K6156601 3 x 1.0 ug
EUR 406.8

Lenti ORF clone of Nfrkb (mGFP-tagged) - Mouse nuclear factor related to kappa B binding protein (Nfrkb)

MR211898L4 10 µg Ask for price

Nfrkb sgRNA CRISPR Lentivector set (Mouse)

K3738301 3 x 1.0 ug
EUR 406.8

NFRKB sgRNA CRISPR Lentivector set (Human)

K1423401 3 x 1.0 ug
EUR 406.8

NFRKB (Myc-DDK-tagged)-Human nuclear factor related to kappaB binding protein (NFRKB), transcript variant 1

RC226572 10 µg Ask for price

NFRKB (Myc-DDK-tagged)-Human nuclear factor related to kappaB binding protein (NFRKB), transcript variant 2

RC215038 10 µg Ask for price

NFRKB Protein Vector (Rat) (pPM-C-HA)

PV285124 500 ng
EUR 1429.2

NFRKB Protein Vector (Rat) (pPB-C-His)

PV285122 500 ng
EUR 1429.2

NFRKB Protein Vector (Rat) (pPB-N-His)

PV285123 500 ng
EUR 1429.2

NFRKB Protein Vector (Rat) (pPM-C-His)

PV285125 500 ng
EUR 1429.2

Lenti ORF clone of Nfrkb (Myc-DDK-tagged) - Mouse nuclear factor related to kappa B binding protein (Nfrkb)

MR211898L3 10 µg Ask for price

NFRKB Protein Vector (Human) (pPM-C-HA)

PV028219 500 ng
EUR 394.8

NFRKB Protein Vector (Mouse) (pPM-C-HA)

PV205300 500 ng
EUR 1278

Lenti ORF particles, Nfrkb (GFP-tagged) - Mouse nuclear factor related to kappa B binding protein (Nfrkb), 200ul, >10^7 TU/mL

MR211898L4V 200 µl Ask for price

NFRKB Protein Vector (Human) (pPB-C-His)

PV028217 500 ng
EUR 394.8

NFRKB Protein Vector (Human) (pPB-N-His)

PV028218 500 ng
EUR 394.8

NFRKB Protein Vector (Human) (pPM-C-His)

PV028220 500 ng
EUR 394.8

NFRKB Protein Vector (Mouse) (pPB-C-His)

PV205298 500 ng
EUR 1278

NFRKB Protein Vector (Mouse) (pPB-N-His)

PV205299 500 ng
EUR 1278

NFRKB Protein Vector (Mouse) (pPM-C-His)

PV205301 500 ng
EUR 1278

Nfrkb 3'UTR Luciferase Stable Cell Line

TU114049 1.0 ml Ask for price

NFRKB 3'UTR Luciferase Stable Cell Line

TU015643 1.0 ml
EUR 1825.2

Nfrkb 3'UTR Luciferase Stable Cell Line

TU213943 1.0 ml Ask for price

Lenti ORF particles, Nfrkb (Myc-DDK-tagged) - Mouse nuclear factor related to kappa B binding protein (Nfrkb), 200ul, >10^7 TU/mL

MR211898L3V 200 µl Ask for price

Nfrkb sgRNA CRISPR Lentivector (Rat) (Target 1)

K6156602 1.0 ug DNA
EUR 184.8

Nfrkb sgRNA CRISPR Lentivector (Rat) (Target 2)

K6156603 1.0 ug DNA
EUR 184.8

Nfrkb sgRNA CRISPR Lentivector (Rat) (Target 3)

K6156604 1.0 ug DNA
EUR 184.8

Nfrkb sgRNA CRISPR Lentivector (Mouse) (Target 1)

K3738302 1.0 ug DNA
EUR 184.8

Nfrkb sgRNA CRISPR Lentivector (Mouse) (Target 2)

K3738303 1.0 ug DNA
EUR 184.8

Nfrkb sgRNA CRISPR Lentivector (Mouse) (Target 3)

K3738304 1.0 ug DNA
EUR 184.8

NFRKB sgRNA CRISPR Lentivector (Human) (Target 1)

K1423402 1.0 ug DNA
EUR 184.8

NFRKB sgRNA CRISPR Lentivector (Human) (Target 2)

K1423403 1.0 ug DNA
EUR 184.8

NFRKB sgRNA CRISPR Lentivector (Human) (Target 3)

K1423404 1.0 ug DNA
EUR 184.8

Lenti-ORF clone of NFRKB (mGFP-tagged)-Human nuclear factor related to kappaB binding protein (NFRKB), transcript variant 1

RC226572L4 10 µg Ask for price

AAP34265-100UG - NFRKB Peptide - N-terminal region

AAP34265-100UG 100ug
EUR 99

ARP34265_P050-25UL - NFRKB Antibody - N-terminal region

ARP34265_P050-25UL 25ul
EUR 99

Lenti-ORF clone of NFRKB (Myc-DDK-tagged)-Human nuclear factor related to kappaB binding protein (NFRKB), transcript variant 1

RC226572L3 10 µg Ask for price

ARP34265_P050 - NFRKB antibody - N-terminal region (ARP34265_P050)

ARP34265_P050 100ul
EUR 389

Lenti ORF particles, NFRKB (Myc-DDK tagged) - Human nuclear factor related to kappaB binding protein (NFRKB), transcript variant 2, 200ul, >10^7

RC215038L3V 200 µl Ask for price

Lenti ORF particles, NFRKB (mGFP-tagged) - Human nuclear factor related to kappaB binding protein (NFRKB), transcript variant 2, 200ul, >10^7 TU/

RC215038L4V 200 µl Ask for price

Lenti ORF particles, NFRKB (mGFP-tagged)-Human nuclear factor related to kappaB binding protein (NFRKB), transcript variant 1, 200ul, >10^7 TU/mL

RC226572L4V 200 µl Ask for price

Lenti ORF particles, NFRKB (Myc-DDK-tagged)-Human nuclear factor related to kappaB binding protein (NFRKB), transcript variant 1, 200ul, >10^7 TU

RC226572L3V 200 µl Ask for price

Nfrkb (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each

SR422607 2 nmol Ask for price

NFRKB (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each

SR303168 2 nmol Ask for price

Nfrkb sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)

K6156605 3 x 1.0 ug
EUR 451.2

Nfrkb sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K3738305 3 x 1.0 ug
EUR 451.2

NFRKB sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K1423405 3 x 1.0 ug
EUR 451.2

Nuclear Factor Related To Kappa B Binding Protein (NFRKB) Antibody

20-abx326280
  • Ask for price
  • Ask for price
  • 100 ug
  • 50 ug

Nuclear Factor Related To Kappa B Binding Protein (NFRkB) Antibody

20-abx173863
  • Ask for price
  • Ask for price
  • 1 mg
  • 200 ug

Nuclear Factor Related To Kappa B Binding Protein (NFRkB) Antibody

20-abx177837
  • Ask for price
  • Ask for price
  • 1 mg
  • 200 ug

Nuclear Factor Related To Kappa B Binding Protein (NFRKB) Antibody

20-abx136034
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Nuclear Factor Related To Kappa B Binding Protein (NFRKB) Antibody

20-abx008933
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ul
  • 200 ul
  • 30 ul

Nuclear Factor Related To Kappa B Binding Protein (NFRKB) Antibody

abx136034-01mg 0.1 mg
EUR 175

Nuclear Factor Related To Kappa B Binding Protein (NFRKB) Antibody

abx326280-100g 100 µg
EUR 250

Nuclear Factor Related To Kappa B Binding Protein (NFRKB) Antibody

abx326280-50g 50 µg
EUR 187.5

Nfrkb sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)

K6156606 1.0 ug DNA
EUR 200.4

Nfrkb sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)

K6156607 1.0 ug DNA
EUR 200.4

Nfrkb sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)

K6156608 1.0 ug DNA
EUR 200.4

Nfrkb sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K3738306 1.0 ug DNA
EUR 200.4

Nfrkb sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K3738307 1.0 ug DNA
EUR 200.4

Nfrkb sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K3738308 1.0 ug DNA
EUR 200.4

NFRKB sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K1423406 1.0 ug DNA
EUR 200.4

NFRKB sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K1423407 1.0 ug DNA
EUR 200.4

NFRKB sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K1423408 1.0 ug DNA
EUR 200.4

Nfrkb - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector

TL706677 5 µg/vial Ask for price

Nfrkb - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector

TL512479 5 µg/vial Ask for price

NFRKB - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector

TL311183 5 µg/vial Ask for price

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) Protein

20-abx654588
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) Protein

abx654588-20g 20 µg
EUR 4525

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) Protein

abx654588-5g 5 µg
EUR 1800

Nfrkb - Rat, 4 unique 29mer shRNA constructs in retroviral untagged vector

TR706677 5 µg/vial Ask for price

Pig Nuclear Factor Related To Kappa B Binding Protein (NFRKB) ELISA Kit

abx361070-96tests 96 tests
EUR 990

Human Nuclear Factor Related To Kappa B Binding Protein (NFRKB) CLIA Kit

20-abx495471
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Nuclear Factor Related To kappa B Binding Protein (NFRKB) CLIA Kit

abx197363-100l 100 µl Ask for price

Human Nuclear Factor Related To kappa B Binding Protein (NFRKB) CLIA Kit

abx197363-50l 50 µl
EUR 618.75

NFRKB - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector

TR311183 5 µg/vial Ask for price

Nfrkb - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector

TR512479 5 µg/vial Ask for price

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit

DLR-NFRkB-Hu 96T
EUR 463
Description: tissue homogenates or other biological fluids.

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit

DLR-NFRkB-Hu-48T 48T
EUR 620.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) in samples from tissue homogenates or other biological fluids.

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit

DLR-NFRkB-Hu-96T 96T
EUR 807.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) in samples from tissue homogenates or other biological fluids.

Human NFRkB(Nuclear Factor Related To Kappa B Binding Protein) ELISA Kit

ELK3777-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human NFRkB. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human NFRkB. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human NFRkB, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human NFRkB in the samples is then determined by comparing the OD of the samples to the standard curve.

Human NFRkB(Nuclear Factor Related To Kappa B Binding Protein) ELISA Kit

ELK3777-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human NFRkB. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human NFRkB. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human NFRkB, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human NFRkB in the samples is then determined by comparing the OD of the samples to the standard curve.

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit

EKN47470-48T 48T
EUR 378.7

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit

EKN47470-5x96T 5x96T
EUR 2569.75

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit

EKN47470-96T 96T
EUR 541

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit

EKU06359-48T 48T
EUR 555.66

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit

EKU06359-5x96T 5x96T
EUR 3770.55

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit

EKU06359-96T 96T
EUR 793.8

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit

DL-NFRkB-Hu 96T
EUR 441
Description: tissue homogenates or other biological fluids.

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit

EK15715 96Т
EUR 768

Sheep Nuclear Factor Related To Kappa B Binding Protein (NFRKB) ELISA Kit

abx364137-96tests 96 tests
EUR 1111.2

Human Nuclear Factor Related To Kappa B Binding Protein (NFRKB) ELISA Kit

abx354438-96tests 96 tests
EUR 848.4

Human Nuclear Factor Related To Kappa B Binding Protein (NFRKB) ELISA Kit

20-abx152519
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit

RD-NFRkB-Hu-48T 48T
EUR 452.7
Description: tissue homogenates and other biological fluids.

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit

RD-NFRkB-Hu-48Tests 48 Tests
EUR 625.2

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit

RD-NFRkB-Hu-96T 96T
EUR 646.7
Description: tissue homogenates and other biological fluids.

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit

RD-NFRkB-Hu-96Tests 96 Tests
EUR 867.6

Human Nuclear Factor Related To Kappa B Binding Protein(NFRkB)ELISA Kit

QY-E03139 96T
EUR 433.2

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit

RDR-NFRkB-Hu-48T 48T
EUR 475.34
Description: tissue homogenates and other biological fluids.

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit

RDR-NFRkB-Hu-48Tests 48 Tests
EUR 652.8

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit

RDR-NFRkB-Hu-96T 96T
EUR 679.04
Description: tissue homogenates and other biological fluids.

Human Nuclear Factor Related To Kappa B Binding Protein (NFRkB) ELISA Kit

RDR-NFRkB-Hu-96Tests 96 Tests
EUR 907.2

High linkage disequilibrium was seen between variants of Han Chinese pedigrees. No important genotype-phenotype correlations have been recognized.These findings could also be influenced by choice, publication bias and the belief that HS is a monogenic dysfunction.

The poor IRR of present phenotype measures suggests restricted utility of present measures. Further investigations into the correlation of scientific phenotypes with inflammatory biomarkers could help in prognostic efforts for this illness.

What’s already identified about this subject? Genotype-phenotype correlation can present info concerning illness pathogenesis and predictions for future illness development, severity or exercise. The identification of such indicators in hidradenitis suppurativa (HS) could be invaluable for sufferers and clinicians alike, given the shortage of biomarkers or scientific predictors of illness.

What does this research add? Sixty-five sequence variants throughout 20 separate genes have been recognized. There was no important correlation between phenotype classification in 4 separate classification schema and gene, mutation kind or impression on Notch signalling.

Utility of present phenotype measurements are restricted. The lack of genotype-phenotype correlation in HS is suggestive that the underlying assumption of inherited HS as a monogenic dysfunction may have revision.

Scroll to Top