Evaluation of a prototype DNA probe test for the noncultural diagnosis of gonorrhea.

Application of a six sigma model to evaluate the analytical performance of urinary biochemical analytes and design a risk-based statistical quality control strategy for these assays: A multicenter study

Background: The six sigma model has been widely used in clinical laboratory quality management. In this study, we first applied the six sigma model to (a) evaluate the analytical performance of urinary biochemical analytes across five laboratories, (b) design risk-based statistical quality control (SQC) strategies, and (c) formulate improvement measures for each of the analytes …

Application of a six sigma model to evaluate the analytical performance of urinary biochemical analytes and design a risk-based statistical quality control strategy for these assays: A multicenter study Read More »

Optimization of the method for analyzing endocytosis of fluorescently tagged molecules: Impact of incubation in the cell culture medium and cell surface wash with glycine-hydrochloric acid buffer

To obtain the therapeutic effect of biological medicines, such as proteins and nucleic acids, these medicines must achieve their intracellular target, such as the cytoplasm, and pass through biological membrane barriers. Endocytosis is an attractive route for the intracellular delivery of such drugs, and various endocytosis inhibitors have been used as tools to study the …

Optimization of the method for analyzing endocytosis of fluorescently tagged molecules: Impact of incubation in the cell culture medium and cell surface wash with glycine-hydrochloric acid buffer Read More »

Bioengineering of LAB vector expressing Haemolysin co-regulated protein (Hcp): a strategic approach to control gut colonization of Campylobacter jejuni in a murine model

Background: Campylobacter jejuni (C. jejuni) is accountable for more than 400 million cases of gastroenteritis each year and is listed as a high-priority gut pathogen by the World Health Organization (WHO). Although the acute infection of C. jejuni (campylobacteriosis) is commonly treated with macrolides and fluoroquinolones, the emergence of antibiotic resistance among C. jejuni warrants …

Bioengineering of LAB vector expressing Haemolysin co-regulated protein (Hcp): a strategic approach to control gut colonization of Campylobacter jejuni in a murine model Read More »

First outbreak of multi-drug resistant tuberculosis (MDR-TB) in Denmark involving six Danish-born cases

Background: Denmark is a tuberculosis (TB) and multi-drug resistant (MDR) TB low-incidence country at 5 and 0.05 cases per 100.000 population, respectively. Until 2018, transmission of MDR-TB was nonexistent except for few pairwise related family-cases. In this study we describe the first MDR-TB outbreak in Denmark. Methods: Based on genotyping of all Mycobacterium tuberculosis (Mtb) culture-positive …

First outbreak of multi-drug resistant tuberculosis (MDR-TB) in Denmark involving six Danish-born cases Read More »

Panbio Nasopharyngeal Testt

Detection of SARS-CoV-2 viral antigen.

Overview To provide an additional layer of protection against COVID-19covid 19 and variants including Omicron, Ontario is launching a holiday testing blitz to offer voluntary rapid antigen screening to individuals free of charge at pop-up sites across the province. This initiative is part of the government’s enhanced COVID-19covid 19 testing strategy to mitigate the increased risk of transmission over the holiday …

Detection of SARS-CoV-2 viral antigen. Read More »

Evaluation of a prototype DNA probe test for the noncultural diagnosis of gonorrhea.

A prototype, nonisotopic, chemiluminescent DNA probe test referred to as the Gen-Probe PACE (Probe Assay-Chemiluminescence Enhanced) system for Neisseria gonorrhoeae (Gen-Probe, San Diego, Calif.) was in contrast with standard Martin-Lewis tradition medium in JEMBEC plates for the laboratory diagnosis of gonorrhea. This 2-h noncultural assay is predicated upon the use of an acridinium ester-labeled DNA probe. The …

Evaluation of a prototype DNA probe test for the noncultural diagnosis of gonorrhea. Read More »

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