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Z-DNA as a Tool for Nuclease-Free DNA Methyltransferase Assay

Methylcytosines in mammalian genomes are the main epigenetic molecular codes that switch off the repertoire of genes in cell-type and cell-stage dependent manners. DNA methyltransferases (DMT) are dedicated to managing the status of cytosine methylation. DNA methylation is not only critical in normal development, but it is also implicated in cancers, degeneration, and senescence. Thus, …

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SARS-CoV-2 RBD of Spike protein GH452R.V1, CAL.20C, L452R – lineage B.1.429 – CAL Variant

A new emerging variant of SARS-CoV-2, called CAL.20C or lineage B.1.429, was recently reported in California (USA). Identified by researchers at Cedars-Sinai Medical Center in July 2020, the variant was initially reported as rare only to resurface later that year (October). The most recent reports indicate that CAL.20C is rapidly replacing the old 20G lineage, …

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InstantBlue

InstantBlue ™ is a ready-to-use Coomassie protein dye for polyacrylamide gels. Its unique mechanism of action stains proteins in 15 minutes leaving a clear background eliminating the need to fix, wash or fade. Ultra-fast staining and one-step procedure High sensitivity with detectable 5 ng bands Bright background with a high signal-to-noise ratio Formulated for safe …

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